Digestive health is the cornerstone of overall well-being, yet millions struggle with issues like bloating, inflammation, and conditions such as irritable bowel syndrome (IBS) or inflammatory bowel disease (IBD). While conventional treatments can help, many are turning to natural remedies like Cannabigerol (CBG) and medicinal mushrooms for support. In this blog, we’ll explore how these two powerhouses might promote a healthier gut, dive into the science behind their effects, and share tips for incorporating them into your routine.
Understanding Digestive Health Challenges
The digestive system is a complex network responsible for breaking down food, absorbing nutrients, and eliminating waste. When it’s out of balance, you might experience symptoms like abdominal pain, irregular bowel movements, or chronic inflammation. Conditions like IBS affect up to 15% of the global population, while IBD, which includes Crohn’s disease and ulcerative colitis, can cause severe inflammation and discomfort. The gut microbiome—a community of trillions of bacteria—plays a key role in digestion, immunity, and even mental health. Supporting this delicate ecosystem is crucial for maintaining digestive harmony.
What is CBG?
Cannabigerol (CBG) is a non-psychoactive cannabinoid found in the cannabis plant, often called the “mother of all cannabinoids” because it’s a precursor to CBD and THC. Unlike THC, CBG won’t get you high, making it an appealing option for those seeking therapeutic benefits without psychoactive effects. CBG interacts with the body’s endocannabinoid system (ECS), a network of receptors that helps regulate functions like digestion, inflammation, and pain perception. By binding to CB1 and CB2 receptors in the gut and nervous system, CBG may help restore balance in the digestive tract.
What Are Medicinal Mushrooms?
Medicinal mushrooms, such as reishi, chaga, and lion’s mane, have been used for centuries in traditional medicine, particularly in Asian cultures. These fungi are packed with bioactive compounds like polysaccharides, beta-glucans, and triterpenoids, which offer a range of health benefits. For digestive health, mushrooms are valued for their prebiotic properties, meaning they feed the beneficial bacteria in your gut, helping to maintain a balanced microbiome. They also have anti-inflammatory and immune-modulating effects, which can support gut healing.
CBG and Digestive Health: What Does the Science Say?
Research on CBG for digestive health is still emerging, but early studies show promising results:
- Anti-Inflammatory Effects: A 2013 study published in Biochemical Pharmacology found that CBG reduced inflammation in a mouse model of IBD. By targeting specific receptors, CBG decreased the production of inflammatory markers, potentially easing symptoms like abdominal pain and diarrhea. Visit Biochemical Pharmacology
- Gut Motility and Pain: CBG may help regulate gut motility (the movement of food through the digestive tract). A 2014 study in Carcinogenesis noted that CBG acts as an antagonist to the TRPM8 receptor, which is involved in inflammation and pain signaling in the gut. This could make CBG a natural option for managing discomfort in conditions like colitis. Visit Carcinogenesis
- Appetite Stimulation: For those with digestive issues that suppress appetite, such as IBD or cancer-related conditions, CBG might help. A 2016 study in Psychopharmacology showed that CBG stimulated appetite in rats, suggesting it could support nutritional intake in humans with appetite loss. Visit Psychopharmacology
While these findings are encouraging, most studies are preclinical (conducted on animals), and more human trials are needed to confirm CBG’s efficacy for digestive health.
Medicinal Mushrooms and Digestive Health: The Research
Medicinal mushrooms have a long history of use for gut health, and modern science is starting to catch up:
- Prebiotic Power: A 2017 review in PMC highlighted that mushrooms like reishi and chaga are rich in polysaccharides, such as beta-glucans, which act as prebiotics. These compounds stimulate the growth of beneficial gut bacteria, like Bacteroidetes and Firmicutes, which help digest food and reduce inflammation. A balanced microbiome can improve gut barrier function, reducing the risk of “leaky gut” and related issues. Visit PMC
- Anti-Inflammatory and Immunomodulatory Effects: A 2021 review in PMC noted that medicinal mushrooms, including reishi, have anti-inflammatory properties that can soothe the gut lining. In clinical trials, mushroom extracts like AndosanTM (a blend of mushrooms) showed mild digestive side effects in cancer patients, but overall safety, suggesting they could be a gentle option for gut support.
- Digestive Enzyme Support: Some mushrooms, like lion’s mane, may enhance the production of digestive enzymes, aiding in the breakdown of food. While direct studies on this are limited, their role in supporting overall gut microbiota health indirectly benefits digestion.
Combining CBG and Medicinal Mushrooms: A Synergistic Approach?
CBG and medicinal mushrooms may complement each other for digestive health. CBG’s anti-inflammatory and pain-relieving properties could address acute symptoms, while medicinal mushrooms work to support long-term gut microbiome balance. For example, CBG might help reduce inflammation in IBD flare-ups, while reishi’s prebiotic effects could help maintain a healthy gut environment to prevent future issues. Additionally, both have antioxidant properties, which can combat oxidative stress—a common factor in chronic digestive conditions.
Anecdotal Evidence and User Experiences
Online communities and social media platforms like X have seen growing chatter about CBG and medicinal mushrooms for digestive health. A 2025 X post shared a user’s experience with CBG oil, noting that it “calmed my IBS symptoms within a week,” particularly reducing bloating and cramping. Another user mentioned combining reishi mushroom tea with CBG, saying it helped with their “gut-brain connection,” improving both digestion and mood. While these stories are encouraging, individual results vary, and it’s always best to consult a healthcare professional before trying new remedies.
At Bristol CBD, we offer a range of products that might support your digestive health journey. Our 20% Gold Full Spectrum CBG Oil—which contains 10% CBD and 10% CBG—is a great option for those looking to harness CBG’s potential anti-inflammatory benefits for the gut while also benefiting from CBD’s soothing effects. For a more concentrated dose, our 23% CBD Paste (2300mg CBD in 10g syringe)—containing approximately 20% CBD and 3% CBG—offers a potent alternative with a balanced cannabinoid profile to support overall wellness. Always start with a low dose and monitor how your body responds.
How to Incorporate CBG and Medicinal Mushrooms into Your Routine
If you’re interested in trying CBG and medicinal mushrooms for digestive health, here are some tips:
- CBG Products: Look for high-quality CBG oils or capsules from reputable brands. Start with a low dose (5-10 mg/day) and gradually increase, paying attention to how your gut responds. Sublingual oils may work faster for symptom relief, while edibles might offer longer-lasting effects.
- Medicinal Mushrooms: Reishi, chaga, and lion’s mane are widely available as powders, capsules, or teas. Add mushroom powder to smoothies or brew a soothing reishi tea before bed to support gut healing overnight.
- Combine with Probiotics: Pairing CBG and mushrooms with probiotics can enhance their gut-supporting effects by introducing beneficial bacteria while the prebiotics in mushrooms feed them.
- Consult a Professional: Always speak with your doctor before starting CBG or medicinal mushrooms, especially if you’re on medications or have a chronic digestive condition. CBG may interact with certain drugs, and mushrooms can sometimes cause mild digestive upset in sensitive individuals.
Things to Consider
- Quality Matters: Choose third-party-tested CBG products and organic medicinal mushrooms to ensure purity and potency.
- Potential Side Effects: CBG is generally well-tolerated, but some users report mild drowsiness or dry mouth. Medicinal mushrooms may cause digestive upset in rare cases, especially if you’re new to them.
- Legal Status: CBG derived from hemp (with less than 0.3% THC) is legal in many regions, but check your local laws. Medicinal mushrooms are widely available as supplements and are generally legal.
The Future of CBG and Medicinal Mushrooms for Digestive Health
The potential of CBG and medicinal mushrooms for digestive health is an exciting area of research. Ongoing studies are exploring CBG’s role in gut inflammation and motility, while clinical trials on mushrooms are investigating their prebiotic and immunomodulatory effects in humans. As more data emerges, we may see these natural remedies become a mainstream option for gut health support. For now, they offer a promising complementary approach for those seeking relief from digestive issues.
Final Thoughts
Digestive health is deeply personal, and finding the right support can make all the difference. CBG and medicinal mushrooms offer a natural way to address inflammation, support the gut microbiome, and promote overall balance. By combining the anti-inflammatory power of CBG with the prebiotic benefits of mushrooms, you might find a holistic solution to your digestive woes. As always, work with your healthcare provider to ensure these remedies fit your needs.
Have you tried CBG or medicinal mushrooms for digestive health? Share your experiences in the comments—we’d love to hear from you!
Disclaimer: This blog is for informational purposes only and not a substitute for medical advice. Always consult a healthcare professional before starting any new treatment, including CBG or medicinal mushrooms.
20% Gold CBG and CBD Full Spectrum Oil
Each bottle contains 10% CBG (cannabigerol) plus 10% CBD (cannabidiol) plus a full spectrum of other cannabinoids and terpenes for the full entourage effect, in a mild tasting golden oil. Bristol CBD oils always come from organically grown hemp. Click here for reviews.
Each bottle contains 1,000mg CBG and 1,000mg CBD. Each drop is 5mg CBG and 5mg CBD.
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10 grams of raw, whole plant, full spectrum CBD paste in a handy syringe. Nothing added or taken away. Simply pure hemp extract just as nature intended. Each syringe contains 23% CBD + 3% CBG and a full spectrum of other cannabinoids and terpenes. Click here for reviews.
Free Royal Mail Tracked 24 delivery on orders over £30. See below for product details and see product images for laboratory certificates.
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